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Introducing Product

Brimonidine topical gel 0.33% under Janu-brim brand name is produced for the first time in Iran by the Janus Pharma Company for treatment of erythema and redness caused by rosacea acne. This product is marked knowledge-based by the Vice President for Science.

Rosacea is a chronic skin disease, usually characterized by erythema and inflammatory lesions in the central part of ​​the face. Although the pathophysiology of the disease is not fully clarified, its key element seems to be inflammation and vascular disorders.

Brimonidine is a selective alpha 2-adrenoceptor agonist, which is more inclined to alpha 2-adrenoceptor than alpha 1. It can reduce patients’ erythema by contraction of small arteries (small arteries and veins).

:Directions

Take a pea-sized amount daily and apply a thin layer evenly on the forehead, chin, nose and cheeks. The amount of medicine used per day should not exceed one gram (pea sized for the whole face).

 

Wash your hands with water immediately after taking the medicine. Consult your doctor or pharmacist if you do not notice any signs of improvement after 5 days of use.

 

Key Points

Frequently Asked Questions

Redness of the skin is one of the side effects of the drug and may occur in some people. If you do not respond to the medicine or if allergic reactions occur, stop taking the medicine and consult your doctor.

So far, no medicine has been known to permanently and definitively eliminate rosacea. Janu-brim gel is a symptomatic treatment to reduce and control skin redness.

The treatment period is 8 weeks. Considering that the effectiveness is through vascular contraction, so the treatment is symptomatic and the redness returns after stopping the treatment.

You can use Janu-brim gel half an hour before leaving the house, and after the gel dries, it is safe to use cosmetics, sunscreen, or moisturizing creams on the skin.

No. Janu-brim has no effect on the demodex parasite. However, patients with rosacea due to demodex can use Janu-brim to control the redness in their face with the doctor’s advice.

The treatment period with Janu-brim is 8 weeks. No resistance has been reported during this period. However, no studies have been done on more than this period.

If the duration of exposure to the sun is less than one hour, you can still use the product despite the reduced effect of the active ingredient. Exposure to the sun for more than an hour or inside the car in hot weather will destroy the formulation, and it is better to prepare a new medicine.

Unfortunately, the structure of your medicinal gel is damaged, and you should buy a new medicine.

Clean the affected area with a tissue and rinse the residue with good water. Do not try to remove the medicine with your tongue or by swallowing.

Accidental contact of Janu-brim gel with the eyes causes inflammation and moderate itching. After contact with the eyes, do not rub the eyes and immediately wash the eyes with plenty of water for at least 15 minutes. While washing, open and close your eyes several times to ensure sufficient washing. See a doctor if eye inflammation persists.

Since the medicine is used topically, the possibility of inhaling it is very low. However, in the case of drug inhalation, take the patient to the open air to breathe fresh air.

If the medicine is swallowed by the patient, a large amount of water or milk should be fed to him immediately to dilute the amount of active ingredients. Then go to the hospital immediately. Do not induce vomiting in any way. The side effects of oral brimonidine are very high, and do not hesitate to see a doctor.

The side effects caused by swallowing Janu-brim topical gel are very serious. These side effects include breathing disorders, severe dizziness, decreased heart rate, diarrhea and vomiting, fainting, and severe itching and swelling.

It can be used for up to 90 days provided the medicine is stored in the conditions stated in the box. However, at the end of 90 days, you can be certain about the stability of Janu-brim by controlling the color and smell of the product and its consistency. Although the weight of the product is such that with proper and regular use, it will last less than 90 days after opening the medicine.

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